Mysteries and blank maps...

"...lived by the admonition of E. T. Jaynes that if you were ignorant about a phenomenon, that was a fact about your own state of mind, not a fact about the phenomenon itself; that your uncertainty was a fact about you, not a fact about whatever you were uncertain about; that ignorance existed in the mind, not in reality; that a blank map did not correspond to a blank territory. There were mysterious questions, but a mysterious answer was a contradiction in terms. A phenomenon could be mysterious to some particular person, but there could be no phenomena mysterious of themselves. To worship a sacred mystery was just to worship your own ignorance.

[...] People had no sense of history, they learned about chemistry and biology and astronomy and thought that these matters had always been the proper meat of science, that they had never been mysterious. The stars had once been mysteries. Lord Kelvin had once called the nature of life and biology - the response of muscles to human will and the generation of trees from seeds - a mystery "infinitely beyond" the reach of science. (Not just a little beyond, mind you, but infinitely beyond. Lord Kelvin sure had gotten a big emotional kick out of not knowing something.) Every mystery ever solved had been a puzzle from the dawn of the human species right up until someone solved it."

Harry Potter and the Methods of Rationality by  Less Wrong